Non-invasive Brain Stimulation for Essential Tremor

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Non-invasive Brain Stimulation for Essential Tremor

BACKGROUND There is increasing interest in the use of non-invasive brain stimulation to characterize and potentially treat essential tremor (ET). Studies have used a variety of stimulation coils, paradigms, and target locations to make these observations. We reviewed the literature to compare prior studies and to evaluate the rationale and the methods used in these studies. METHODS We perform...

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"Asleep" deep brain stimulation for essential tremor.

OBJECT Deep brain stimulation (DBS) performed under general anesthesia ("asleep" DBS) has not been previously reported for essential tremor. This is in part due to the inability to visualize the target (the ventral intermediate nucleus [VIM]) on MRI. The authors evaluate the efficacy of this asleep technique in treating essential tremor by indirect VIM targeting. METHODS The authors retrospecti...

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Does non-invasive brain stimulation reduce essential tremor? A systematic review and meta-analysis

Essential tremor (ET) is the most common age-related disease leading to abnormal tremulous behaviors in the upper and lower extremities. Non-invasive brain stimulation (NIBS) may be an effective ET therapy by modulating the oscillating network of the brain. The current systematic review and meta-analysis examined the effects of NIBS interventions on tremor symptoms in ET patients. Our comprehen...

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Non-invasive Central and Peripheral Stimulation: New Hope for Essential Tremor?

Essential tremor (ET) is among the most frequent movement disorders. It usually manifests as a postural and kinematic tremor of the arms, but may also involve the head, voice, lower limbs, and trunk. An oscillatory network has been proposed as a neural correlate of ET, and is mainly composed of the olivocerebellar system, thalamus, and motor cortex. Since pharmacological agents have limited ben...

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Functional connectivity targeting for deep brain stimulation in essential tremor.

BACKGROUND AND PURPOSE Deep brain stimulation of the thalamus has become a valuable treatment for medication-refractory essential tremor, but current targeting provides only a limited ability to account for individual anatomic variability. We examined whether functional connectivity measurements among the motor cortex, superior cerebellum, and thalamus would allow discrimination of precise targ...

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ژورنال

عنوان ژورنال: Tremor and Other Hyperkinetic Movements

سال: 2017

ISSN: 2160-8288

DOI: 10.5334/tohm.377